Antibodies against epididymal glycoproteins block fertilizing ability in rat
نویسندگان
چکیده
منابع مشابه
Relations between the fertilizing ability, motility and metabolism of epididymal spermatozoa.
This paper compares the principal modifications taking place in spermatozoa during epididymal transit in several species. The relations between changes in the epididymal medium and modifications in the metabolism, motility and/or fertility of spermatozoa are reviewed with particular reference to spermatozoon forward motility. The fertilizing ability of motile testicular and epididymal spermatoz...
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Ram spermatozoa from the distal caput, corpus, and cauda epididymis and ejaculated spermatozoa were artificially inseminated in 170 ewes which had been treated with an ovulatory dose of PMSG 61 ! 4 hrs previously. Results were expressed as the percent of ewes pregnant 18 days after insemination (F = with positive progesterone assay/ Q inseminated) and embryonic survival (ES = ewes lambing/ preg...
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Several decades ago it was reported that when adult male rats were exposed to a single injection of 50 mg/kg body weight ethane dimethanesulfonate (EDS) and mated with untreated females, average litter size was significantly reduced as early as 2 weeks later. Recently, we demonstrated that EDS exerts multiple effects in the epididymis of adult rats. Some of these effects were independent of red...
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Cholesterol, being the starting point of steroid hormone synthesis, is a long known modulator of both female and male reproductive physiology especially at the level of the gonads and the impact cholesterol has on gametogenesis. Less is known about the effects cholesterol homeostasis may have on postgonadic reproductive functions. Lately, several data have been reported showing how imbalanced c...
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We prepared murine monoclonal antibodies to porcine platelet membrane glycoprotein (GP) lb and GP llb/Illa for further study of the porcine hemostatic mechanism. One monoclonal antibody, designated PP3-4C. blocked Ristocetin-induced platelet agglutination and caused 80% inhibition of Ristocetin-induced ‘25l-von Willebrand factor (vWF) binding to porcine platelets at a concentration of 1 2 gsg l...
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ژورنال
عنوان ژورنال: Reproduction
سال: 1984
ISSN: 1470-1626,1741-7899
DOI: 10.1530/jrf.0.0720467